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Donate Life South Carolina, a state-authorized nonprofit 501 (c)3 organization, is solely responsible for managing the organ, eye and tissue donor registry. We are dedicated to saving the lives of thousands of South Carolinians awaiting life-saving transplants. 

Our Mission and Vision


Our mission is to promote organ and tissue donation for transplantation and provide patient assistance for South Carolina recipients. Donate Life South Carolina maintains the South Carolina Organ, Eye and Tissue Registry.  

Our vision is to work collaboratively with partners so that all individuals who are in need of a transplant receive one. 

Our History

Founder Lawrence F. McManus, MD: Larry McManus, was an orthopedic surgeon, a transplant patient, an activist, and ultimately, the visionary of what is now Donate Life South Caroline (DLSC). Originally named Gift of Life Trust Fund (GLTF), the statewide not-for-profit organization promoting organ and tissue donation changed its name in 2006 in keeping with the national Donate Life America branding effort. 

It Was Personal

In 1989, Dr. McManus learned that his liver had failed. He was told he could expect 12 to 18 months of life without treatment – and the only treatment and chance for long-term survival was a liver transplant. In May 1991, Larry was placed on the national waiting list to receive a liver. After waiting 180 days he received the “Gift of Life” through an organ donor. 

Experience into Action

As a result of their experiences, Larry and his wife, Kitty, founded DLSC. The organization’s mission was to educate South Carolinians about the importance of becoming organ and tissue donors. The couple’s challenges in navigating the transplant process inspired them to include a patient assistance component later.

A Lasting Legacy

The passing of Act 262 officially established Donate Life South Carolina in 1996. Dr. McManus passed on June 19, 2001, but his legacy continues through the work of the DLSC staff, Board, and his wife, Kitty McManus. The final years of his life were marked by accomplishments and deep gratitude for the donors whose gift enabled him to achieve great things during his time here. In his words, “What greater act of love and charity can one show than by becoming an organ and tissue donor? I thank my donors every day for their generosity.” 

What can YOU make possible?